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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Ciclopirox targets cellular bioenergetics and activates ER stress to induce apoptosis in non-small cell lung cancer cells

Fig. 4

CPX treatment promotes aerobic glycolysis in NSCLC cells. A Alteration of ECAR in H1299 and 95D cells with the treatment of CPX (0, 5, 10, 20 μM). B Glycolytic capacity of NSCLC cells with the treatment of CPX (0, 5, 10, 20 μM). C H1299 and 95D cells with the treatment of CPX (0, 5, 10, 20 μM), and cells were collected and the whole cell lysate was examined by Western blot analysis. D Glucose uptake in H1299 and 95D cells treated with CPX (0, 5, 10, 20 μM). Data were presented as mean ± SD (n = 3, **for p < 0.01, ***for p < 0.001, ****for p < 0.0001)

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