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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: An NF-κB/OVOL2 circuit regulates glucose import and cell survival in non-small cell lung cancer

Fig. 8

Clinical relevance of OVOL2, NF-κB signaling and GLUT1. A Representative immunostaining of OVOL2, pP65 and GLUT1 in NSCLC tissue samples and the corresponding adjacent normal tissue samples. Scale bars: 20 μm. B Relative percentages of the immunoreactivity scores for OVOL2, pP65 and membrane GLUT1 staining in 85 NSCLC tissue samples and the corresponding adjacent normal tissues. Fisher’s exact test was used to analyze categorical variables (p < 0.001). C Correlation between OVOL2 and pP65 protein levels. D Correlation between OVOL2 and membrane GLUT1 protein levels. E Correlation between pP65 and membrane GLUT1 protein levels. Pearson correlation analysis was performed on the data in C to E (r and p values are shown on the corresponding plots)

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