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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: The granulosa cell response to luteinizing hormone is partly mediated by YAP1-dependent induction of amphiregulin

Fig. 6

YAP1 is recruited to the Areg promoter following hCG stimulation. ChIP-qPCR analyses were performed on GCs isolated from eCG-primed WT mice before (black lines) or after (grey lines) 60 min of hCG stimulation to evaluate the enrichment of YAP1 on the Areg promoter. The no antibody controls (NoAb) appear as dotted lines. n = 4 biological replicates/timepoint, one replicate contains the GCs of 4 mice. Data are expressed as percentage of input DNA. Two-way ANOVA (Sidak’s post hoc test): *P ≤ 0.05, ****P ≤ 0.0001

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