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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Endothelial colony-forming cell-derived exosomal miR-21-5p regulates autophagic flux to promote vascular endothelial repair by inhibiting SIPL1A2 in atherosclerosis

Fig. 5

miRNA cargo in ECFCs-exosomes. A Top 30 miRNAs expression in ECFCs-exosomes. The pie chart illustrates the miRNA composition of ECFC exosomes. B Validation of miRNA expression in ECFC exosomes. Biological replicates = 3, and technical replicates = 3. C Altered expression levels of miRNA in HMECs with or without ox-LDL. Biological replicates = 3, and technical replicates = 3. D Expression of miR-21-5p was detected by quantitative real-time PCR. Exos ECFCs-exosomes. Biological replicates = 3, and technical replicates = 3. N.S. not significant; significant differences between different treatment groups are indicated as *P < 0.05

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