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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Endothelial colony-forming cell-derived exosomal miR-21-5p regulates autophagic flux to promote vascular endothelial repair by inhibiting SIPL1A2 in atherosclerosis

Fig. 3

ECFC-derived exosomes rescue autophagic flux in ox-LDL-treated HMECs. A Expression of autophagy-related proteins (LC3I, LC3II, and p62) in HMECs after different treatments was detected by western blot assay. Biological replicates = 3, and technical replicates = 1. B Representative images of cells infected with Ad-mCherry-GFP-LC3B adenovirus after different treatments. Scale bars = 100 μm. Exos ECFCs-exosomes, Bafi A1 Bafilomycin A1. Biological replicates = 3, and technical replicates = 1. Significant differences between different treatment groups are indicated as *P < 0.05

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Cell Communication and Signaling

ISSN: 1478-811X