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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: UHMK1-dependent phosphorylation of Cajal body protein coilin alters 5-FU sensitivity in colon cancer cells

Fig. 4

Effects of UHMK1 knockdown on coilin phosphorylation and 5-FU sensitivity in HCT-8 cells. a Co-immunoprecipitation assay for coilin serine phosphorylation in UHMK1 knockdown HCT-8 cells. b CB morphology and statistics in UHMK1 knockdown HCT-8 cells. c CCK8 assays for cell growth of UHMK1 knockdown cells. d Survival of UHMK1 knockdown HCT-8 cells following 5-FU treatments (0, 1, 5, 10, 20 and 40 μg/ml) for 48 h. Data were presented as the mean ± SD, n = 6. ** p < 0.01

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Cell Communication and Signaling

ISSN: 1478-811X