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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Lactobacillus improves the effects of prednisone on autoimmune hepatitis via gut microbiota-mediated follicular helper T cells

Fig. 7

Prednisone and Lactobacillus inhibit Tfh response in EAH mice through MyD88. A The level of IL-21 in the serum of WT or MyD88 − / − EAH mice by treatment of prednisone + Lactobacillus was assessed by ELISA. B, C The portion of CD4+CXCR5+ICOS+ Tfh cells in the PBMCs of WT or MyD88 − / − EAH mice by treatment of prednisone + Lactobacillus was detected by flow cytometry analysis. D The protein levels of IL-6, IL-10, KGF-1, and KGF-2 in the serum of WT or MyD88 − / − EAH mice by treatment of prednisone + Lactobacillus were assessed by ELISA. The data are presented as the mean ± SEM. *P < 0.05 vs EAH, ns indicates no significance

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Cell Communication and Signaling

ISSN: 1478-811X