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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Lactobacillus improves the effects of prednisone on autoimmune hepatitis via gut microbiota-mediated follicular helper T cells

Fig. 5

Prednisone and Lactobacillus inhibit Tfh response in EAH mice through CD103. A The level of IL-21 in the serum of WT or CD103 − / − EAH mice after treatment of prednisone + Lactobacillus was determined by ELISA. B, C The frequencies of CD4+CXCR5+ICOS+ Tfh cells in the PBMCs of WT or CD103 − / − EAH mice after treatment with prednisone + Lactobacillus was determined by flow cytometry analysis. D The protein levels of IL-6, IL-10, KGF-1, and KGF-2 in the serum of WT or CD103 − / − EAH mice after treatment with prednisone or prednisone + Lactobacillus. The data are presented as the mean ± SEM. *P < 0.05 vs EAH, ns indicates no significance

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Cell Communication and Signaling

ISSN: 1478-811X