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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: CPNE1 promotes non-small cell lung cancer progression by interacting with RACK1 via the MET signaling pathway

Fig. 5

Knockdown of RACK1 inhibited the proliferation and motility of A549 and HCC827 cells. A The mRNA and protein level of RACK1 was decreased in RACK1 knockdown cells. B Clonogenic assays were performed to assess cell proliferation, and quantified on the right. C CCK-8 assays were also performed to analyse cell proliferation. D Transwell assays were performed to analyse the cell motility abilities. Data represent the mean (± SD) of three independent experiments, and unpaired t test was used to verify the statistical significance. E, F Western blot analysis of relevant protein levels in RACK1 knockdown cells compared to control cells, with quantification on the right. *P < 0.05; **P < 0.01; ***P < 0.001

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Cell Communication and Signaling

ISSN: 1478-811X