Fig. 1

Knockdown of CPNE1 inhibited the proliferation and motility of A549 and HCC827 cells. A The mRNA and protein level of CPNE1 was downregulated in CPNE1 knockdown cells. B The clonogenic assays were performed to assess cell proliferation. C CCK-8 assays were also performed to analyse cell proliferation. D Transwell assays were performed to analyse the cell motility abilities. Data represent the mean (± SD) of three independent experiments, and unpaired t test was used to verify the statistical significance. *P < 0.05; **P < 0.01; ***P < 0.001