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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Heterocellular N-cadherin junctions enable nontransformed cells to inhibit the growth of adjacent transformed cells

Fig. 6

Nontransformed cells stabilize p120-catenin expression in adjacent Src transformed cells. a Src transformed (MEC-Src and MEC-SrcPdpn), nontransformed wild type (MEC), and cadherin knockout (MEC-CdhKo) mouse embryonic cells were plated alone (scale bar = 200 microns). b Src transformed cells without (MEC-Src) and with (MEC-SrcPdpn) forced PDPN expression stained with DiI (red) were plated with nontransformed wild type (MEC) or cadherin deficient (MEC-CdhKo) cells at a 1:30 ratio. Cultures were grown for 24 h, stained with Hoechst (blue) and p120 catenin antibody (green), and visualized by confocal microscopy as indicated (scale bars = 50 μm)

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Cell Communication and Signaling

ISSN: 1478-811X