Fig. 5From: Scavenger receptors in host defense: from functional aspects to mode of actionSCAR-G on immune cell activates various immune related pathways like Th1 immune response via activation of IL12 and IFN-γ. On binding to gram-negative and gram-positive bacteria this receptor activates phagocytosis of bacteria into mature APCs following activation of IL12, TNF-α and p40 that helps to convert Th0 into Th1 cellsBack to article page