Fig. 4From: Scavenger receptors in host defense: from functional aspects to mode of actionSCAR-F1 on binding to diverse ligands like B-glucans, OmpA, NS3 in presence of TLR2 activates proinflammatory response, Antigen cross-presentation and viral uptake. On interaction with TLR4 in presence of LPS it activates MAP kinases following activation of various transcriptional factors like p38 and JNK that mediate extracellular release of IL6, TNF-α and INF-βBack to article page