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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: Mechanism of MyD88S mediated signal termination

Fig. 7

MyD88 ID is essential for myddosome formation in human primary macrophages. mCherry labeled MyD88 variants (indicated on top of the figure) were overexpressed in human monocyte-derived macrophages (hMDMs) differentiated from peripheral blood mononuclear cells (PBMCs) and imaged by fluorescence microscopy. Formation of supramolecular organizing centers (SMOCs) is indicated by arrowheads. Diffuse distribution of the transgene with no indication of SMOC formation is evident for MyD88S and Ala2

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Cell Communication and Signaling

ISSN: 1478-811X