Fig. 5
PMVs improved the function of VEC via CTGF delivery. A The expression of CTGF and PCNA in LPS-stimulated VECs treated by modified PMVs (n = 3). B CCK8 proliferation of LPS-stimulated VECs treated by modified PMVs (n = 6). C Scratch experiment of LPS-stimulated VECs treated by modified PMVs, the representative images are shown (n = 5, bar = 100 μm). D Tube formation of LPS-stimulated VECs treated by modified PMVs, the representative images are shown (n = 5, bar = 50 μm). E Statistical analysis of the tube length in D (n = 5). Ctl: normal group; LPS: LPS group; PMV: PMV-treated LPS group; PMVCTGF−up: CTGF-upregulated PMV + LPS group; PMVCTGF−down: CTGF-downregulated PMV + LPS group; PMVvehicle: CTGF-mock-transfected PMV + LPS group. ***P < 0.001, **P < 0.01