Fig. 6

Hypothesis validation on RNA-sequencing mice model data. Genes which contributed to core enrichment are marked on heatmaps with green frames. Heatmaps depict the genes that comprise the pathway with red tiles representing increased expression in WFS versus controls. A Enrichment plot and heatmap of Reactome mitochondrial protein import Gene Set performed on transcriptomics data on mice hypothalamic. B Enrichment plot and heatmap of Reactome respiratory electron transport performed on transcriptomics data on mice hypothalamic. C Enrichment plot and heatmap of Reactome mitochondrial protein import Gene Set performed on transcriptomics data on mice hippocampi. D Enrichment plot and heatmap of Reactome respiratory electron transport performed on transcriptomics data on mice hippocampi