Fig. 1
From: Pharmacologic targeting of the P-TEFb complex as a therapeutic strategy for chronic myeloid leukemia
Wogonin induced erythroid differentiation in chronic myeloid leukemia cell lines and primary CML cells. a K562 and KU-812 cells were treated with wogonin (0, 5, 10, 20, 40 and 80 μM) for 120 h. The expression of CD41 and CD61 was detected by flow cytometry analyses. b Quantification of the expression of CD41/CD61. Columns represent the mean from three parallel experiments (mean ± SD), compared with control group. c K562 and KU-812 cells were treated with wogonin (0, 5, 10, 20, 40 and 80 μM) for 120 h. The expression of CD71 and GPA was detected by flow cytometry analyses. d Quantification of the expression of CD41/CD61. Columns represent the mean from three parallel experiments (mean ± SD). *p < 0.05, **p < 0.01, ***p < 0.001, compared with control group. e #1 Primary CML cells were treated with wogonin (0, 20, 40 and 80 μM) for 120 h. The expression of CD71 and GPA was detected by flow cytometry analyses. f Quantification of the expression of CD41/CD61. Columns represent the mean from three parallel experiments (mean ± SD). *p < 0.05, **p < 0.01, compared with control group