Fig. 7
From: Hhex inhibits cell migration via regulating RHOA/CDC42-CFL1 axis in human lung cancer cells
Hhex enhanced interaction of RHOGDIA with RHOA/CDC42. a HHEX siRNA-RHOGDIA were co-transfected into A549. Cell lysate was immunoprecipitated with anti-FLAG antibody, Hhex, RHOA were detected by western blot. The images are representative of three independent experiments with similar results. b HHEX siRNA and pcDNA3.1-RHOGDIA were co-transfected into Calu-1. Cell lysate was immunoprecipitated with anti-FLAG antibody, Hhex, RHOA were detected by western blot. The images are representative of three independent experiments with similar results. c A549 cells were conducted same treatments as (a), Hhex and CDC42 were detected by western blot. The images are representative of three independent experiments with similar results. d Calu-1 cells were conducted same treatments as (a), Hhex and CDC42 were detected by western blot. The images are representative of three independent experiments with similar results