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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway

Fig. 8

Inhibiting PI3K-Akt pathway in glioblastoma-derived EVs-treated mNPCs reversed elevated NPC migration. A Wortamnnin significantly reversed U87-EVs-elevated migration cell numbers in U87-EVs-treated mNPCs in the transwell assay. B Wortamnnin significantly reversed U87-EVs-elevated relative width of scratch in U87-EVs-treated mNPCs in wound healing assay. Results are presented as the mean ± SD of three independent experiments. *p < 0.05, ***p < 0.001. Scale bar, 100 μm (A) and 200 μm (B)

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Cell Communication and Signaling

ISSN: 1478-811X