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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Effect of HSP90AB1 and CC domain interaction on Bcr-Abl protein cytoplasm localization and function in chronic myeloid leukemia cells

Fig. 6

HSP90 inhibitor 17AAG combined with protein nucleus export inhibitor LMB could enhance the killing ability when targeting CML cells. K562 and K562/G01 cells were cultured in control group, 17AAG group, IM group and 17AAG-LMB group respectively a, b FCM assays the effect of 17AAG combined with LMB inhibitor on CML cell cycle. c, d FCM assays the effect of 17AAG combined with LMB inhibitor on anti-apoptotic ability of CML cells

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