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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Patient-derived scaffolds influence secretion profiles in cancer cells mirroring clinical features and breast cancer subtypes

Fig. 3

Secretome profiles of patient-derived scaffolds. a All detected proteins (n = 72) secreted in the PDSs cultivated with MCF7 cells (n = 57), each dot represent one PDS. The same PDSs are used for all proteins. b All detected proteins (n = 121) secreted in the PDSs cultivated with MDA-MB-231 cells (n = 53), each dot represent one PDS. The same PDSs are used for all proteins. Only proteins with a secretion value over the limit of detection in a minimum of 10% of the investigated PDSs were included in the analysis. A negative medium control was subtracted from each protein before normalized to the total protein secretion of each PDS. c Schematic picture of three representative secreted proteins (CA9, DCN and PlGF) for three PDSs cultivated with MCF7 cells

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Cell Communication and Signaling

ISSN: 1478-811X