Fig. 2
From: Systemic and topical administration of spermidine accelerates skin wound healing
The systemic and topical administration of SPD enhances G-uPAR production and uPAR cleavage. a The serum uPA concentration in the mice treated with systemic or topical SPD was measured using ELISA (n = 4 mice). b–d The expression of G-uPAR, uPAR, uPARD2D3, and GAPDH in the wound sites was measured using western blot analysis. Skin tissue lysates (20 µg/protein) were used for the experiment and analyzed by immunoblotting. Chemiluminescent signals were quantified using ImageJ software and normalized to GAPDH signals. *Indicates a statistically significant differences; p < 0.05. ***Indicates a statistically significant difference; p < 0.005