Fig. 1
From: Developing PspCas13b-based enhanced RESCUE system, eRESCUE, with efficient RNA base editing
dPspCas13b-RESCUE and dRanCas13b-RESCUE systems mediated exogenous mRNA A-to-I or C-to-U editing in 293T cells. a Schematic representative of the engineered dPsp/dRanCas13b-RESCUE system. b A-to-I RNA editing efficiency analysis of NES-guided dPsp/dRanCas13b-RESCUE systems. Bars represent the mean ± SEM. Different asterisks represent significant differences as follows: *p < 0.05; **p < 0.01; ***p < 0.001. c C-to-U RNA editing efficiency analysis of NES-guided dPsp/dRanCas13b-RESCUE systems. Bars represent the mean ± SEM. “***”p < 0.001; ns, no significance