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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: FZD5 prevents epithelial-mesenchymal transition in gastric cancer

Fig. 1

FZD5 maintains gastric cancer cell epithelial-like phenotype. a A heat map showing the correlation of FZD5 with EMT-related factors in gastric cancer cell lines was generated from CCLE database. b A pathway related to FZD5 in gastric cancer was shown by GO pathway enrichment analysis using TCGA database. c FZD5 expression in MKN45 cells was detected by Western blot. d and e CDH1 and Vim expression in MKN45 cells was detected by Real-time PCR and Immunofluorescence. **P < 0.01, ***P < 0.001, vs shCtrl. Scalebar: 50 μm. f MKN45 cells were stained with Phalloidin. Scalebar: 50 μm. g and h Migration of MKN45 cells was analyzed by Transwell. ***P < 0.001, vs shCtrl. Scalebar: 50 μm. All experiments were performed in triplicate

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