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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity

Fig. 4

Effects of FA incubation on lipid accumulation, ultrastructures and autophagy in yellow catfish hepatocytes at 48 h. a The contents of TG and NEFA, and LD staining and fluorescence intensity of Bodipy. b Representative TEM image of hepatocytes. Nu: nucleus, LD: lipid droplet, arrowheads: mitochondria (m), black box: autophatic vesicles, oval frame: lipid clearance by autophagy. c Western blot analysis of Beclin1, LC3B-II and P62. d Immunofluorescence analysis of LC3B-II. Values are means ± SEM (n = 3). Asterisks (∗) indicate significant differences between the control and FA group (p < 0.05)

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Cell Communication and Signaling

ISSN: 1478-811X