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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I

Fig. 1

Effects of ME, HNK, MGN and MHNK on human oral cancer cells and normal human bronchial epithelial (NHBE) cells proliferation. a Representative cell growth curves of CAL 27 upon treatment with various doses of ME. b Cell images corresponding to panel A, at the time point indicated by the vertical dashed line. c Dose-response effects of ME on cell confluence. The indicated concentrations of HNK, MGN, and MHNK are those contained in the 11.7 μg/ml ME treatment. d Representative cell growth curves upon treatment with vehicle or 20 μM of each compound. e Cell images corresponding to panel d, at the time point indicated by the vertical dashed line. f Dose-response antiproliferative effects of each of the three active compounds found within ME. g Effects of HNK, MGN and MHNK (20 μM each) and the mixture of all three agents (Combo, 20 μM each) on the proliferation of two human oral cancer cell lines (SCC4 and CAL27) and normal human bronchial epithelial (NHBE) cells

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Cell Communication and Signaling

ISSN: 1478-811X