SNP rs12982687 affects binding capacity of lncRNA UCA1 with miR-873-5p: involvement in smoking-triggered colorectal cancer progression

Table 1 Comparison of basic clinical features between colorectal cancer patients and healthy controls

Clinical feature	Case		Control		χ²	P value
Clinical feature	Number	Percentage	Number	Percentage	χ²	P value
Age (years)
≥ 50	423	55.51%	735	52.20%
<50	339	44.49%	673	47.80%	2.18	0.140
Gender
Female	189	24.80%	301	21.38%
Male	573	75.20%	1107	78.62%	3.32	0.069
Pathological classification
Poor differentiation	216	28.35%	–
Moderate differentiation	305	40.03%
Well differentiation	241	31.63%
TNM classification
I	32	4.20%	–
II	371	48.69%
III	268	35.17%
IV	91	11.94%
Smoking
Yes	592	77.69%	849	60.30%
No	170	22.31%	559	39.70%	67.04	< 0.001
Alcohol
Yes	563	73.88%	778	55.26%
No	199	26.12%	630	44.74%	72.68	< 0.001
Fruit intake, > 1 serving/day
Yes	329	43.18%	821	58.31%
No	433	56.82%	587	41.69%	45.46	< 0.001
Vegetable intake, > 1 serving/day
Yes	481	63.12%	990	70.31%
No	281	36.88%	418	29.69%	11.70	< 0.001
Foods or beverages temperature
Hot	494	64.83%	784	55.68%
Warm	268	35.17%	624	44.32%	17.09	< 0.001
Smoked or pickled foods intake
Yes	478	62.73%	834	59.23%
No	284	37.27%	574	40.77%	2.53	0.112

The bold results indicated there is a statistically significance when its p value < 0.05.

ISSN: 1478-811X