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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: SNP rs12982687 affects binding capacity of lncRNA UCA1 with miR-873-5p: involvement in smoking-triggered colorectal cancer progression

Fig. 3

Single nucleotide polymorphism (SNP) rs12982687 (C > T) affected invasion, migration and epithelial-mesenchymal transition (EMT) of colorectal cancer (CRC) cells. a Invasive capability of SW620 and SW480 cell lines was assessed when miR-873-5p expression was up-regulated and down-regulated. *: P < 0.05 when compared with miR-NC group. b The migratory potency of SW620 and SW480 cell lines was compared among miR-NC, miR-873-5p mimic and miR-873-5p inhibitor groups. *: P < 0.05 when compared with miR-NC group. c Expressions of EMT-related proteins were detected within SW620 and SW480 cell lines of miR-NC, miR-873-5p mimic and miR-873-5p inhibitor groups. *: P < 0.05 when compared with miR-NC group

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Cell Communication and Signaling

ISSN: 1478-811X