Fig. 1

Association of single nucleotide polymorphisms (SNPs) in lncRNA UCA1 with survival of colorectal cancer (CRC) patients. a The secondary structure of UCA1 varied between allele C (left) and allele T (right) of rs12982687. The red block was indicative of changes in the secondary structure of UCA1. b The secondary structure of UCA1 differed between allele A (left) and allele G (right) of rs11085996. The red block was indicative of changes in the secondary structure of UCA1. c Four-year survival was compared among CRC patients who carried distinct genotypes of rs11085996 (up) and rs12982687 (down). d MiRNAs that possibly bound to UCA1 were quantified within CRC tissues and adjacent non-tumor tissues. The miRNAs were deemed as down-regulated when their -log10 (false discovery rate) was > 1.2 and log2 (fold change) was <− 0.5. e Correlations of UCA1 expression with miRNA levels were displayed by establishing correlation matrix. f Survival curves were depicted to assess the association of UCA1, miR-873-5p, miR-1207-5p and miR-584 expressions with CRC prognosis