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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Expression of apoptosis repressor with caspase recruitment domain (ARC) in familial adenomatous polyposis (FAP) adenomas and its correlation with DNA mismatch repair proteins, p53, Bcl-2, COX-2 and beta-catenin

Fig. 2

Representative examples of nuclear ARC staining. Most of the examined FAP adenomas showed overexpression of nuclear ARC. Only 6.6% exhibited no or very little nuclear ARC expression (score 0; a). In 62.7% of FAP adenomas, ARC was overexpressed in 10–75% of nuclei (score 1; b) and in 30.7% of adenomas, overexpression was present in over 75% of nuclei (score 2; c)

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