Table 1 Specific information for the crystal structure of hPVR extracellular domain
From: Computer-aided design of PVR mutants with enhanced binding affinity to TIGIT
NO | PDBID | Organism(s) | Method | Resolution (Ã…) | R-value | PVR length | Notations | Journal |
|---|---|---|---|---|---|---|---|---|
1 | 3URO | Homo Sapiens | X-ray Diffraction | 3.5 | 0.305 | V30-Y242(213) | N105D, N120S, N188Q, N218Q, N237S | PNAS, 2008 |
2 | 4FQP | Homo Sapiens | X-ray Diffraction | 3.6 | 0.248 | D28-P333(306) | 0 | Nat Struct Mol Biol,2012 |
3 | 3UDW | Homo Sapiens | X-ray Diffraction | 2.9 | 0.251 | D28-A143 (116) | 0 | PNAS,2012 |
4 | 1DGI | Homo sapiens, Human poliovirus 1 | Electron Microscopy | 22 | – | D28-V329(302) | 0 | PNAS,2000 |
5 | 1NN8 | Homo sapiens, Human poliovirus 1 Mahoney | Electron Microscopy | 15 | – | D28-V329(302) | 0 | J. Virol,2003 |
6 | 3EPF | Homo sapiens, Poliovirus type 2 strain Lansing | Electron Microscopy | 9 | – | V30-Y242(213) | N105D, N120S, N188Q, N218Q, N237S | PNAS,2008 |
7 | 3EPD | Homo Sapiens, Human poliovirus 3 | Electron Microscopy | 9 | – | V30-Y242(213) | N105D, N120S, N188Q, N218Q, N237S | PNAS,2008 |
8 | 3EPC | Homo sapiens, Human poliovirus 1 Mahoney | Electron Microscopy | 8 | – | V30-Y242(213) | N105D, N120S, N188Q, N218Q, N237S | PNAS,2008 |
9 | 3J9F | Homo sapiens, Human poliovirus 1 Mahoney | Electron Microscopy | 9 | – | D28-A143 (116) | 0 | J. Virol,2015 |
10 | 3J8F | Homo sapiens, Human poliovirus 1 Mahoney | Electron Microscopy | 3.7 | – | D28-P333(306) | 0 | J. Virol,2015 |