Fig. 4From: Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunitiesCaspase-1 PTMs and the enzymes responsible for their regulation. Empirically validated enzymes which are responsible for the PTM regulation of Caspase-1. “+” indicates that the enzyme promotes the activation of Caspase-1, while “−” indicates repression of its function. Amino acid residues shown above refer to human Caspase-1, those in brackets refer to mouse Caspase-1 residuesBack to article page