Fig. 2
From: Inhibition of the Otub1/c-Maf axis by the herbal acevaltrate induces myeloma cell apoptosis
AVT induces c-Maf degradation via the ubiquitin-proteasomal pathway. a–b RPMI-8226 and LP1 cells were incubated with AVT for 4 h, followed by the treatment of the proteasomal inhibitor MG132 (a) or the lysosomal inhibitor chloroquine (CHQ) (b). The cell lysates were subjected to WB assays. c RPMI-8226 and LP1 cells were treated with AVT 4 h followed by CHX treatment for indicated periods. All cell lysates were subjected to WB assays as indicated