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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

Fig. 3

Enriched proteins in MyoX, TenX and FibX. a Number of proteins with over ±2-fold mean differential abundance in small EV samples, when cells of origin were compared (FDR p < 0.1). b-d Heatmaps showing the abundance pattern across individual samples of proteins with over ± ≥ 2-fold mean differential abundance in b TenX compared to MyoX, c TenX compared to FibX, and d MyoX compared to FibX. The range of fold change is represented by the colour key. See Supplementary Data 6 for heatmap values. e-g Top 10 significantly enriched terms, ranked by their enrichment scores, that were overrepresented in highly abundant proteins of e MyoX (391 proteins), f TenX (185 proteins), and g FibX (104 proteins). See Supplementary Data 7 for the full enrichment analysis results

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Cell Communication and Signaling

ISSN: 1478-811X