Fig. 2

Variability in small EV samples. a Heatmap of Pearson correlation coefficient (r) for pairwise comparison of each MyoX, TenX and FibX sample. Each square represents a single comparison with the intensity of colour denoting the r-value according to the number within. High r-values (red squares) denote high correlation and green squares denote low correlation between samples, respectively. b Principal component analysis (PCA) showing the first two principle components (PC1 and PC2). Numbers inside the circles indicate the sample numbers. c Heatmap showing hierarchical clustering of samples based on their protein abundances ranked by SD. See Supplementary Figure 4 for heatmap values