Table 1 Exosomes derived from mesenchymal stem cells and the respective cargo
From: Exosomal microRNAs derived from mesenchymal stem cells: cell-to-cell messages
Cargo | Disease | Source (type of MScs) | Detection method | Mode (in vitro, in vivo, human) | Ref |
|---|---|---|---|---|---|
Paclitaxel | Pancreatic adenocarcinoma | Mouse MSC | – | In vitro | [97] |
Paclitaxel | Breast cancer | Human MSCs | IVIS Lumina III imaging system | In vitro, In vivo | [115] |
anti-miR-9 | Glioblastoma multiforme | Human bone marrow | Flow cytometry, Western blot | In vitro | [106] |
miRNA-143 | Osteosarcoma | Human bone marrow | – | In vitro | [107] |
CXCR4 | Myocardial Infarction | Rat bone marrow | Real-time QPCR | In vivo, In vitro | [108] |
Akt, PDGF | Myocardial Infarction | Human umbilical cord MSCs | Western blot | In vivo | [109] |
HLA-G, TGF- beta and IL-10 | GVHD | Human bone marrow | Cytokine release assay | In vivo, In vitro | [112] |
TRAIL | Different cancer cell lines | Human MSCs | Immunofluorescence staining | In vitro | [114] |