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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Mitochondrial DNA drives noncanonical inflammation activation via cGAS–STING signaling pathway in retinal microvascular endothelial cells

Fig. 4

Immunofluorescence of ER, ERGIC and Golgi and STING after mtDNA stimulation of RMECs. Figure A1-C1: normal control groups; Figure A2-C2: mtDNA stimulation groups. Green was STING and blue was DAPI. Red was ER, ERGIC and Golgi in figure A2–2, B2–2 and C2–2, respectively. In normal control group, STING was dispersive and co-localization with ER maker. In mtDNA-stimulated group, STING was aggregated specks formed in the perinuclear region and partly co-localization in ERGIC and Golgi makers

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Cell Communication and Signaling

ISSN: 1478-811X