Table 3 .
Common GO among vWAT sWAT BM | GO vWAT specific | GO sWAT specific | GO BM specific | |
|---|---|---|---|---|
COMMON AND SPECIFIC GENE ONTOLOGY ENTITIES IN ND SAMPLES | ||||
GO BIOLOGICAL PROCESS | Arp2/3 complex-mediated actin nucleation | Carbohydrate metabolic process | Response to toxic substance | Carbohydrate metabolic process |
Actin filament organization | Response to toxic substance | Response to inorganic substance | Cellular lipid metabolic process | |
Cell motility | Response to inorganic substance | Small molecule metabolic process | Regulation of leukocyte chemotaxis | |
Collagen fibril organization | Drug metabolic process | Glutathione metabolic process | Regulation of leukocyte migration | |
Ribosomal large unit assembly | Small molecule metabolic process | Cellular lipid metabolic process | Granulocyte chemotaxis | |
Translation | Tissue remodeling | Amino acid metabolism | Negative regulation of cell death | |
Regulation of peptidase activity | Response to hypoxia | Chemokine-mediated signaling pathway | ||
Response to endoplasmic reticulum stress | Tissue remodeling | |||
Chaperone-mediated protein folding | Angiogenesis | |||
Proteasome-mediated ubiquitin dependent protein catabolic process | Endothelial cell proliferation | |||
Positive regulation of epithelial cell proliferation | ||||
Response to oxidative stress | Regulation of leukocyte chemotaxis | |||
Glucose 6-phosphate metabolic process | Regulation of leukocyte migration | |||
Glycolytic process | Granulocyte chemotaxis | |||
ATP metabolic process | Bone morphogenesis | |||
Chondrocyte differentiation | ||||
Regulation of cellular response to growth factor stimulus | ||||
Negative regulation of cell death | ||||
GO PATHWAYS | Cytoskeletal regulation by Rho GTPase | FGF signaling pathway | FGF signaling pathway | Pyruvate metabolism |
Integrin signaling pathway | EGF receptor signaling pathway | EGF receptor signaling pathway | Plasminogen activating cascade | |
Glycolysis | ||||
Pentose phosphate pathway | ||||
De novo purine biosynthesis | ||||
Blood coagulation | ||||
Inflammation mediated by chemokine and cytokine signaling pathway | ||||
CHANGES IN HFD SAMPLES | ||||
GO BIOLOGICAL PROCESS | Drug metabolic process ABSENT | Cellular lipid metabolic process ABSENT | Ribosomal large subunit assembly ABSENT | |
Small molecule metabolic process ABSENT | Endothelial cell proliferation ABSENT | |||
Response to Interleukin-1 | Translation ABSENT | |||
Carbohydrate metabolic process ABSENT | ||||
Cellular lipid metabolic process ABSENT | ||||
ATP metabolic process ABSENT | ||||
Bone morphogenesis | ||||
Chondrocyte differentiation | ||||
Tissue morphogenesis | ||||
ERK1 and ERK2 cascade | ||||
Response to Interleukin-1 | ||||
GO PATHWAYS | Blood coagulation ABSENT | CCKR signaling map | Pyruvate metabolism ABSENT | |
FGF signaling pathway ABSENT | Plasminogen activating cascade | De novo purine biosynthesis ABSENT | ||
EGF receptor signaling pathway ABSENT | Gonadotropin-releasing hormone receptor pathway | |||