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Table 1 mRNA expression profiles in MDA-MB-231 cells

From: RelB sustains endocrine resistant malignancy: an insight of noncanonical NF-κB pathway into breast Cancer progression

Gene name

Ctrl

RelB-KO

log2(RelB-KO/Ctrl)

up-or-down

P value

VIM

1105.77

968.23

−0.1916

down

0.0411

CDH11

14.2157

5.1362

−1.4687

down

5.00E-05

ZEB1

8.9261

4.7115

−0.9219

down

5.00E-05

SNAI1

0.6309

0.474

−0.4124

down

0.1663

MMP1

108.85

7.6109

−3.8382

down

5.00E-05

MMP9

0.7118

0.3904

−0.8663

down

0.0037

MMP28

1.134

0.2263

−2.3250

down

0.0008

JUN

53.297

154.57

1.5361

up

0.0001

Hsp70

1.5236

3.1771

1.0602

up

0.0001

DMBT1

0.9316

1.9726

1.0822

up

5.00E-05

SMAD2

7.1095

7.0939

−0.0032

unchanged

0.9734

  1. VIM vimentin, CDH11 cadherin 11, ZEB1 zinc finger E-box-binding homeobox 1, SNAI1 snail1, MMP1 matrix metallopeptidase 1, MMP9 matrix metallopeptidase 9, MMP28 matrix metallopeptidase 28, JUN Jun proto-oncogene (AP-1 transcription factor), Hsp70 heat shock protein 70, DMBT1 deleted in malignant brain tumor 1 (tumor suppressor), SMAD2 a member in TGF-B/Smad signaling family