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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: RelB sustains endocrine resistant malignancy: an insight of noncanonical NF-κB pathway into breast Cancer progression

Fig. 1

The correlation between RelB and aggressiveness of BCa. a, b TCGA database (GEO accession: GSE11121) was analyzed to examine the correlation between mRNA expression profiles of RelA and RelB and BCa occurrence and over survival of patients. c BCa tumor tissues with different pathological grades and normal breast tissues were screened by IHC using NF-κB antibodies. The Luminal group was characterized as ER-positive and HER2-negative low-grade genotype; HER2+ group was assessed as a middle-grade genotype with high tumor growth; TNBC group was determined as a high grade. d The levels of RelB in TNBC tumors vs. ER-positive BCa tumors were quantified, β-actin-normalized images were plotted

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Cell Communication and Signaling

ISSN: 1478-811X