Fig. 4

Differences in microbial enrichment during immunotherapy. The Circos diagram illustrates the different effects of different members of the microbiota in the treatment of ICIs. Blue bands represent members of the microbiota that are enriched during the treatment of effective ICIs. Red bands represent members of the microbiota that are enriched during the treatment of ineffective ICIs. The numbers in parentheses are the source of the reference. (1) Chaput et al. [111] (2) Frankel et al. [115] (3) Gopalakrishnan et al. [123] (4) Matson et al. [122] (5) Routy et al. [155] (6) Routy et al. [113]. (7) Temraz et al. [156]