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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Gastrin-releasing peptide induces fibrotic response in MRC5s and proliferation in A549s

Fig. 4

GRP induces myofibroblast differentiation by inducing Wnt signalling in MRC5 cells. Figure shows the protein bands of total β-catenin, non-phospho (active) β-catenin, Dkk1, Wnt4, Wnt5a, and Wnt7a (a), the changes at protein levels of total β-catenin (b), active β-catenin (c), Dkk1 (d), Wnt4 (e), Wnt5a (f) and Wnt 7a (g), and the alterations at the gene expression of CTNNB1, GSK3B, AXIN, LEF1, and DKK1 (h). P values are *p < 0.05, **p < 0.01 and ***p < 0.001 compared to Time (0 h); +p < 0.05, ++p < 0.01 and +++p < 0.001 compared to Time (24 h); #p < 0.05, ##p < 0.01 and ###p < 0.001 compared to Time (48 h)

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