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Table 2 Association between clinicopathological factors and Fibronectin and p53 IHC scores in OCCCa/OHGSeCa

From: Upregulation of fibronectin following loss of p53 function is a poor prognostic factor in ovarian carcinoma with a unique immunophenotype

 

Fibronectin IHCscore

 

p53 IHCscore

High (3)

Low (3<)

p-value

High (6)

Low (6<)

p-value

 

n

n (%)

n (%)

 

n (%)

n (%)

 

Age

<58

61

14 (23.0)

47 (77.0)

0.7

23 (37.7)

38 (62.3)

0.6

(years)

58

66

12 (18.2)

54 (81.8)

29 (44.0)

37 (56.0)

Clinical

I

40

7 (17.5)

33 (82.5)

0.7

4 (10.0)

36 (90.0)

< 0.0001

FIGO stage

II / III / IV

87

19 (21.8)

68 (78.2)

48 (55.2)

39 (44.8)

Histology

OCCCa

69

20 (29.0)

49 (71.0)

0.01

6 (8.7)

63 (91.3)

< 0.0001

 

OHGSeCa

58

6 (10.3)

52 (89.7)

46 (79.3)

12 (20.7)

Tumor size

<11.2

82

11 (13.4)

71 (86.6)

0.01

41 (50.0)

41 (50.0)

0.008

(cm)

11.2

45

15 (33.3)

30 (66.7)

11 (24.4)

34 (75.6)

LN

Positive

27

11 (40.7)

16 (59.3)

0.008

15 (55.6)

12 (44.4)

0.1

metastasis

Negative

100

15 (15.0)

85 (85.0)

37 (37.0)

63 (63.0)

Distant

Positive

12

4 (33.3)

8 (66.7)

0.4

10 (83.3)

2 (16.7)

0.004

metastasis

Negative

115

22 (19.1)

93 (66.7)

42 (36.5)

73 (63.5)

  1. LN lymph node, n number of cases