Fig. 7From: Ethanol-activated CaMKII signaling induces neuronal apoptosis through Drp1-mediated excessive mitochondrial fission and JNK1-dependent NLRP3 inflammasome activationThe schematic model for mechanism involved in EtOH-induced neuronal apoptosis. EtOH-induced NLRP3 inflammasome activation inhibits the mitophagy, which increases the accumulation of mitochondrial ROS by excessive fission leading to neuronal apoptosisBack to article page