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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: The role of Wnt/β-catenin-lin28a/let-7 axis in embryo implantation competency and epithelial-mesenchymal transition (EMT)

Fig. 5

The function of Wnt in embryo implantation is mediated through lin28a/let-7. a The efficiency of lin28a siRNA knockdown in blastocysts by immunostaining. b The relative lin28a mRNA level in lin28a siRNA knockdown embryo. c The relative expression of let-7a in lin28a knockdown but Wnt activation blastocyst. d Embryo attachment rate on fibronectin when embryo Wnt was inhibited and/or let7a was knockdown. e Embryo attachment rate on fibronectin when embryo Wnt was inhibited by DKK and/or lin28a was overexpressed (lin28a-TG). Data are means ± s.d. (N = 3–5), bar = 20 μm, p < 0.05 “*”, p < 0.01 “**”

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Cell Communication and Signaling

ISSN: 1478-811X