Cell Communication and Signaling

Table 3 Univariate and multivariate analyses of prognostic factors for 5-year OS of patients with CRC

From: Effect of CIP2A and its mechanism of action in the malignant biological behavior of colorectal cancer

Variable	Univariate analysis		Multivariate analysis		P
Variable	5 year-OS	P	HR	CL (95%)	P
Gender		0.551			NS
Female	70.6
Male	75.2
Age		0.856			NS
≥ 65	74.6
< 65	72.8
Location		0.644			NS
Colon	74.7
Rectum	73.5
T stage		0.007			NS
T1-T2	82.4
T3-T4	68.1
N stage		0.013			NS
N0	78.1
N1-N2	63.6
M stage		0.041			NS
M0	74.4
M1	62.1
TNM stage		0.001			0.030
I-II	79.0		1
III-IV	65.6		1.263	1.023–1.559
Histological grade		0.561			NS
Well	81.9
Moderately	72.2
Poorly	75.0
CEA		0.030			0.000
≥ 5	69.6		1
< 5	80.3		0.410	0.256–0.646
CA19–9		0.323			NS
≥ 37	71.7
< 37	79.2
Family history		0.619			NS
No	74.5
Yes	69.2
Liver metastasis		0.000			0.000
No	77.3		1
Yes	12.8		10.718	6.011–19.111
CIP2A		0.002			0.024
Low expression	79.3		1
High expression	64.2		1.565	1.060–2.310

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