Fig. 2From: Identification of a selective inhibitor of IDH2/R140Q enzyme that induces cellular differentiation in leukemia cellsMolecular dynamics (MD) simulations of IDH2/R140Q_CP-17, IDH2/R140Q_α-KG and IDH2/WT_CP-17 systems. a Evolution of RMSDs during 200 ns MD simulations. b Evolution of the Ile116-Leu289′ distances and the Ile116-Phe148-Leu289′ angles (measured on Cα atoms) in monomers A and B during MD simulationsBack to article page