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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: miR-544 promotes maturity and antioxidation of stem cell-derived endothelial like cells by regulating the YY1/TET2 signalling axis

Fig. 8

Overexpression of miR-544 promotes the function of iEClCs. a qPCR assay of the expression of mRNA of key factors involved in the serotonergic synapse stimulating pathway in each group of iEClCs. **p < 0.01 vs. miR-mut; t test; n = 3. b Western blot analysis of the expression of key factors in the serotonergic synapse stimulating pathway in each group of iEClCs. c Angiogenesis assay of each group of iEClCs in the extracellular matrix. **p < 0.01 vs. miR-mut; t test; n = 3. d Transwell assay. **p < 0.01 vs. miR-mut; t test; n = 3. e ATP levels in the iEClCs of each group. **p < 0.01 vs. miR-mut; t test; n = 3. f SOD levels in the iEClCs of each group. **p < 0.01 vs. miR-mut; t test; n = 3. g Flow cytometry showing the proportions of ROS-positive iEClCs of each group. **p < 0.01 vs. miR-mut; t test; n = 3

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Cell Communication and Signaling

ISSN: 1478-811X