Fig. 5
From: FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer
FOXE1 repressed glycolysis in vivo and FOXE1 expression is negatively correlated with18F-FDG PET/CT SUVmax value in CRC patients. a and b Representative photographs of 18F-FDG PET/CT scans of mice injected with HCT116-FOXE1-KD#1 and control(NC). The SUVmax was significantly higher in the HCT116-FOXE1-KD#1 group than in the control group (P < 0.05). c and d Representative photographs of 18F-FDG PET/CT scans and the corresponding FOXE1 IHC stains of CRC specimens. Patients with low expression of FOXE1 (red points) showed significantly higher SUVmax than patients high FOXE1 expression (blue points)