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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Deletion of low-density lipoprotein-related receptor 5 inhibits liver Cancer cell proliferation via destabilizing Nucleoporin 37

Fig. 1

Knockdown of LRP5 inhibits the proliferation of HepG2 cells. a Representative image of HepG2 cells following siRNA knockdown of LRP5 (three distinct siRNA targeting different segment of LRP5 ORF), LRP6 or β-catenin for 48 h (left). n = 3. Quantification of total cell count. *** P < 0.001, n.s., no significance, compared to siRNA control cells (right). b CCK8 and MTT assays of cell proliferation and cell viability in HepG2 cells following siRNA knockdown of three distinct siRNA targeting LRP5 ORF. ** P < 0.01, *** P < 0.001, n.s., no significance, compared to siRNA control cells

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